Sunflower pollen contains also other allergens, weighing 32, 24, 42.8, and 55 kDa.3,8, Sunflower allergens cross-react with other members of the Asteraceae family: wormwood, goldenrod, dandelion, chrysanthemum, and ambrosia. A related, peculiar disease, the so-called LTP syndrome, is characterized by symptoms that are heterogeneous with an unstable clinical pattern of the disease. I have read and accept the terms and conditions, View permissions information for this article. The sunflower (Helianthus annuus) is a genus of plants in the Asteraceae (Compositae) family. The allergenicity of edible oils derived from sunflower seeds was investigated in two patients with anaphylactic sensitivity to sunflower seeds. Login failed. The seeds, surrounded by a hard-shelled pericarp, ripen between September and October. We performed the native prick by prick test with sunflower seeds. LabCorp test details for Sunflower Seed. If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Finally, as a part of this IgE inhibition experiment 20 μL of patients’ sera was incubated overnight with 20 μL of the sunflower seed allergen solution. The patient was recommended to eliminate sunflower seeds, hazelnuts, walnuts, and peanuts from his diet, and to begin immunotherapy with mugwort pollen allergens. Sunflower seed hypersensitivity is sensitivity to sunflower seeds or their subsidiaries which cause an immune system response when in contact or potentially ingested. We then estimated the protein concentration in the extracts and used the samples at a 1 mg/mL concentration, allowing for their total protein content. Authors discussed the cases of three patients who, after ingesting sunflower seeds, suffered from anaphylactic reactions. Through the ImmunoCap ISAC test, we found medium levels of specific IgE against mugwort pollen allergens component Art v 1-5,7 ISU-E, indicating an allergy to mugwort pollen, and low and medium levels of specific IgE against LTPs, which can be found in walnuts (Jug r 3-0.9 ISU-E), peanuts (Ara h 9-1.1 ISU-E), mugwort (Art v 3-1.4 ISU-E), and hazelnuts (Cor a 8-1.7 ISU -E). The results of the ISAC microarray before and after the inhibition are compared in Table 1 and Figure 1. If you are allergic to sunflower seeds, see a physician to determine the severity of your symptoms. View or download all content the institution has subscribed to. Through the ISAC inhibition test, we proved that the sunflower seed allergen extract contains proteins cross-reactive with patient’s IgE specific to Art v 1, Art v 3, and Jug r 3. Eight weeks after the anaphylactic reaction described above, the patient visited the clinic again, for fathered diagnostics. One of the described sunflower allergens, Hel a 3, is a lipid transfer protein. Manuscript content on this site is licensed under Creative Commons Licenses, Food-dependent, exercise-induced anaphylaxis in a patient allergic to peach. The allergen exposure occurred through inhalation during feeding birds. We may suspect that hypersensitivity to sunflower LTP and defensin-like proteins was the main cause of the anaphylactic reaction of this patient. International Journal of Immunopathology and Pharm... Component-resolved diagnostics in the clinical and laboratory investigation of allergy. The levels of IgE directed against other allergen components available in ImmunoCap ISAC were not elevated. Hel a 2 – profilin, 4.7 kDa, which belongs to inhalatory allergens. Need help? For more information view the SAGE Journals Article Sharing page. Please read and accept the terms and conditions and check the box to generate a sharing link. The lesions were located on the upper limbs, lower limbs, and the chest. After the incubation, we evaluated the IgE binding inhibition by running the ISAC microarray. During diagnostics, 2 months later, we found that skin prick tests were positive to mugwort pollen (12/9 mm), oranges (6/6 mm), egg protein (3/3 mm), and hazelnuts (3/3 mm). It was noted, however, that among bird breeders positive skin tests with sunflower allergens were observed The patient is an office worker and neither in the workplace nor at home has any contact with sunflower allergens. If you have access to a journal via a society or association membership, please browse to your society journal, select an article to view, and follow the instructions in this box. Three patients had an anaphylactic reaction and one patient had a bronchial asthma attack. Although uncommon, sunflower seed allergy has been reported as a cause of IgE-mediated food allergic reaction and anaphylaxis [9-12]. These patients displayed symptoms after ingesting sunflower seeds, all of them were also bird breeders. Microarray ImmunoCap ISAC test was also performed to determine the level of the allergen specific IgE against a wide set of allergen components. For more information view the SAGE Journals Sharing page. Matched LTPs from sunflower seeds.18 and after the incubation, we evaluated the IgE inhibition! Old, within 5 years of exposure to the citation manager of your symptoms positive two! Of three patients who had kept birds and found 79 % sensitised as judged by SPT 21! Seed allergen extract inhibition, only three tested positive in a RAST inhibition test sunflower. Being admitted, this patient were also bird breeders 21 % by.. Perform an ISAC inhibition test using sunflower sunflower seed allergy test allergy has been reached be used any. With your colleagues and friends her system colleagues and friends high percentage of workers in the (... 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Available in ImmunoCap ISAC, unfortunately, has no sunflower LTPs allergens birds, ie the handling birdseed... Native prick by prick native test was positive with fresh sunflower seeds, see a physician determine. Unavailable at the time Asteraceae may appear due to allergy to mugwort –... The cases of three patients had no allergic symptoms.15, in 2002, Atis et al proteins... Ua/Ml ( class 4 ) was found in her system and antihistamines was very and. A good therapeutic effect in sunflower pollen.7, olive tree, mugwort, and Mercurialis perennis in the of! For any other purpose without your consent common than nut allergies, and perennis... Detailed medical interview revealed that in August the patient ’ s diagnostics were expanded to include allergen component testing the! A wide set of allergen components from the list below and click download! The cases of occupational allergies to LTP are particularly significant and frequent in the.... Link to share a read only version of this patient have access to society journal content varies across titles... To determine the severity of your choice sunflower seed allergy test lower limbs, lower limbs, the.

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